Revolutionizing parasitic disease control & transforming health through innovative vaccines

Antigen Variation as a Paradigm Shift in Vaccine Development: Revolutionizing Prevention and Treatment of Parasite Infections.

Cost – Effective

No more needles, no need for refrigeration systems

VacciMed-Oral GmbH is a German company specializing in developing oral vaccines for human and veterinary medicine. Founded in 2021, VacciMed-Oral GmbH is a biotechnology startup company dedicated to revolutionizing the field of vaccination against protozoan parasites and related microorganisms. We aim to develop innovative oral vaccines that effectively combat infections caused by pathogens known for their antigenic variation, such as Giardia lamblia, Trypanosoma brucei, and Tritrichomonas foetus, among many others.

VacciMed-Oral aims to provide safer, more efficient, and long-lasting solutions for preventing and treating these diseases by harnessing the power of inducing antigenic variation within these pathogens and generating cell populations expressing the entire repertoire of potential surface antigens, which are used as vaccines that generate a robust protective immune response.

The aim is to achieve products that can reach the largest possible population and thus improve the quality of life by being more efficient in production, distribution, and storage.

Outstanding advantages of oral vaccines

The developed and patented strategy has been shown to generate long-lasting systemic and mucosal protective responses.

The oral route of administration provides many benefits over traditional injectable vaccination:

  • It achieves greater public acceptance, especially among children, as it is a painless strategy, thus achieving higher vaccination coverage.
  • By dispensing without the use of syringes and not requiring a cold chain for its conservation, it achieves more equitable access to the community since it allows its administration without the need for trained medical personnel, which is critical in regions with a deficient health system, in regions under war or geographically isolated.
  • They do not present a risk of cross-infection by contaminated needles in patients and health personnel.
  • By omitting the use and disposal of disposable supplies such as syringes, cotton wool, etc., they result in more hygienic and environmentally friendly measures.
  • Another advantage is that the patented strategy is made up of “modules” that can be assembled, thus offering great versatility for the development of new vaccines against a wide range of microorganisms using biotechnology tools applied to human and veterinary health.
  • Finally, when vaccines are administered orally, they are exposed to the mucosal immune system, which generates a systemic response, as well as a response in mucous membranes (gastrointestinal tract, respiratory tract, etc.) which are the main site of entry of SARS-COV-2, among others, conferring a more complete protection. In addition, a valuable fact to highlight is that VLPs are classified as subunit vaccines since they do not contain the entire microorganism, but lack the genetic material of the virus and are therefore safer than attenuated or inactivated vaccines, allowing their application to immuno-compromised persons (newborns, pregnant or immuno-suppressed).

Antigen Variation Technology

Our commitment spans both human and veterinary populations affected by protozoan parasites.

Clinical Validation

Rigorous pre-clinical and clinical trials validate the safety and efficacy of our vaccines.

Veterinary Sector Focus

Broadening our reach and making a difference in diverse fields. such as livestock and animal health.

Contact Us

Are you ready to embark on a transformative journey? Look no further. Our cutting-edge biotechnology company invites you to join hands with us.

Bonn, Germany

Tel: +49 0 1768-235-3039

E-Mail: info@vaccimed-oral.com